Cardiac bypass, a procedure frequently used to treat cardiovascular disease, is best performed with the patient’s own tissue. Unfortunately for many patients, this is not an option, so engineered grafts are used to mimic the patient’s native tissue. Currently, many of the engineered grafts implanted into small diameter blood vessels are prone to mechanical and biochemical problems. Thus, Team VESSEL seeks to create viable grafts for small blood vessels by biochemically modifying silk fibroin, a promising biomaterial. We hope to increase both the strength and biocompatibility of vascular grafts through our research.
We need funding to purchase materials such as the silkworm cocoons from which we derive the silk, as well as various reagents to develop the silk into the final graft product. Unfortunately, many of these lab materials are very expensive. With your support, we will be able to buy these materials that are essential to the success of our project. Every donation makes a difference and we appreciate your support in advance.
For more information please visit our team website at http://teamvessel.wix.com/teamvessel
Gifts in support of the University of Maryland are accepted and managed by the University of Maryland College Park Foundation, Inc., an affiliated 501(c)(3) organization authorized by the Board of Regents. Contributions to the University of Maryland are tax deductible as allowed by law. Please see your tax advisor for details.
This contribution will allow us to purchase syringes, which are necessary in the first step of the silk extraction process.
This contribution will allow us to purchase flasks, which are important for our experiment and growing cells.
This contribution will allow us to purchase solution with which we extract silk.
This contribution will allow us to purchase silkworm cocoons, which is the source of the silk we use.
This contribution will allow us to purchase chemical reagents, which are necessary in the silk extraction process.
This contribution will allow us to purchase Matrigel, a gel that is necessary to aid the growth of our cells.
This contribution will allow us to purchase cells with which we can begin biochemical testing.
This contribution will allow to purchase materials to create an electrospinner, which will electrospin the silk fibroin into a graft shape.